منابع مشابه
Genomic Discoveries and Personalized Medicine in Neurological Diseases.
In the past decades, we have witnessed dramatic changes in clinical diagnoses and treatments due to the revolutions of genomics and personalized medicine. Undoubtedly we also met many challenges when we use those advanced technologies in drug discovery and development. In this review, we describe when genomic information is applied in personal healthcare in general. We illustrate some case exam...
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Technology for high-throughout scanning of the human genome and its encoded proteins have rapidly developed to allow systematic analyses of human disease. Application of these technologies is becoming an increasingly effective approach for identifying the biological basis of genetically complex neurological diseases. This review will highlight significant findings resulting from the use of a mu...
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Exertional dyspnoea is commonly an early feature in respiratory disease; however, neurological disease may limit mobility and, as a consequence, preclude this symptom. Diagnosis of respiratory dysfunction resulting from neurological disease may therefore require a higher index of clinical suspicion or the application of specific tests; this exercise is worthwhile if it allows advance detection ...
متن کاملThe role of glia in neurological disease
Glial cells form a network in the central nervous system to support neurons and interact with them. The glia consist essentially of astrocytes that help with the nutrition of neurons and react in some cases of injury, oligodendrocytes that produce myelin, and microglia that are derived from the haemopoietic system and are concerned with the immunological defense of the nervous system. Experimen...
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From the Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD (C.N.R.); and the Department of Human Genetics, University of Utah Health Sciences Center, Salt Lake City (L.B.J.). Address reprint requests to Dr. Rotimi at the National Institutes of Health Center for Research on Genomics and Global Health, 12 South...
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ژورنال
عنوان ژورنال: Human Genetics
سال: 2011
ISSN: 0340-6717,1432-1203
DOI: 10.1007/s00439-011-1001-1